Fetal Vascular Origins of Bronchopulmonary Dysplasia
نویسندگان
چکیده
منابع مشابه
Fetal origins of neonatal lung disease: understanding the pathogenesis of bronchopulmonary dysplasia.
IN THE EARLY 1990s, Barker and colleagues (4) proposed that early events occurring before birth could produce later onset cardiovascular disease in the adult. This “fetal origins hypothesis” sparked the beginning of a new way of thinking among clinical and basic scientists. Over the years, numerous reports have added to this idea that a key to understanding complex human diseases is to consider...
متن کاملImpaired pulmonary vascular development in bronchopulmonary dysplasia.
Bronchopulmonary dysplasia (BPD), the chronic lung disease associated with preterm birth, results from the disruption of normal pulmonary vascular and alveolar growth. Though BPD was once described as primarily due to postnatal injury from mechanical ventilation and oxygen therapy after preterm birth, it is increasingly appreciated that BPD results from antenatal and perinatal factors that inte...
متن کاملBronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) continues to be the most common and most important complication in preterm infants with RDS. The incidence varies from 20 to 60 % in preterm infants whose weight are < 1500 gram. The presence of BPD is often associated with significant mortality and short term and long term morbidity, including growth failure and neurodevelopment delay. The exact mechanism and p...
متن کاملBronchopulmonary dysplasia.
Bronchopulmonary dysplasia (BPD) is the most common chronic respiratory disease that results from complications related to the lung injury during the treatment of respiratory distress syndrome, or develops in older infants when abnormal lung growth occurs. The definition and classification of BPD have changed since the original diagnosis was established many years ago. The incidence of BPD cont...
متن کاملBronchopulmonary dysplasia.
Introduction Many advances in neonatology in the last several decades have allowed for the resuscitation, support, and survival of more preterm infants. The mortality associated with respiratory disease in this population of micropremies has been altered significantly by the use of antenatal corticosteroids, postnatal surfactant, improved respiratory support technology, and enhanced nutritional...
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ژورنال
عنوان ژورنال: The Journal of Pediatrics
سال: 2017
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2017.03.024